U.S. Federal Innovation 17: 3D Cell Imaging at the Nano Level
A tomogram of a cell.
Funded by the U.S. National Center for Research Resources (NCRR), the Boulder laboratory for 3-D electron microscopy of cells has develops methods for imaging diverse cells and tissues in 3D at a resolution of ~ 5 nanometers (nm). (A virus is 30-50 nm in size. DNA is 2.5 nm thick.) The goal of the laboratory is to push its resolution down to 2 nm and set the stage for imaging functioning cells at the best possible resolution. Sources: The Boulder Laboratory for 3-D Electron Microscopy of Cells and Introduction to Size and Scale.